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While tirzepatide is not a hormone medication, it can affect the body in ways that influence hormones, ovulation, and the menstrual cycle

Three key genetic regions include GLP1R (appetite and glucose sensing), FTO (metabolic adaptation and fat mass), and MC4R (energy expenditure and satiety)

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Despite various delivery mechanisms being tested (e.g., pulmonary, buccal, and sublingual), low bioavailability and uncertainty in terms of safety has limited the development and, as such, almost all available insulins are injectable